| Tuesday, 26th October 2010 | 19:00 Uhr | SC Victoria Hamburg  |
: |  VfL Wolfsburg
|
1:3 (0:1) | |
| Tuesday, 26th October 2010 | 19:00 Uhr | TuS Koblenz  |
: |  Hertha BSC
|
2:1 (0:0) | |
| Tuesday, 26th October 2010 | 19:00 Uhr | SpVgg Greuther Fürth  |
: |  FC Augsburg
|
1:3 n.V., 2:4 (1:0) | |
| Tuesday, 26th October 2010 | 19:00 Uhr | 1. FC Köln  |
: |  TSV 1860 München
|
3:0 (0:0) | |
| Tuesday, 26th October 2010 | 20:30 Uhr | FC Bayern München  |
: |  SV Werder Bremen
|
2:1 (1:1) | |
| Tuesday, 26th October 2010 | 20:30 Uhr | FSV Frankfurt  |
: |  FC Schalke 04
|
0:1 (0:1) | |
| Tuesday, 26th October 2010 | 20:30 Uhr | FC Energie Cottbus  |
: |  SC Freiburg
|
2:1 (1:0) | |
| Tuesday, 26th October 2010 | 20:30 Uhr | 1. FC Kaiserslautern  |
: |  DSC Arminia Bielefeld
|
3:0 (2:0) | |
| Wednesday, 27th October 2010 | 19:00 Uhr | Hallescher FC  |
: |  MSV Duisburg
|
0:3 (0:2) | |
| Wednesday, 27th October 2010 | 19:00 Uhr | Eintracht Frankfurt  |
: |  Hamburger SV
|
5:2 (3:1) | |
| Wednesday, 27th October 2010 | 19:00 Uhr | Alemannia Aachen  |
: |  1. FSV Mainz 05
|
2:1 (1:0) | |
| Wednesday, 27th October 2010 | 19:00 Uhr | TSG Hoffenheim  |
: |  FC Ingolstadt 04
|
1:0 (0:0) | |
| Wednesday, 27th October 2010 | 20:30 Uhr | Chemnitzer FC  |
: |  VfB Stuttgart
|
0:2 n.V., 1:3 (0:0) | |
| Wednesday, 27th October 2010 | 20:30 Uhr | Kickers Offenbach  |
: |  Borussia Dortmund
|
4:2 n.P., 0:0 (0:0) | |
| Wednesday, 27th October 2010 | 20:30 Uhr | Borussia M´gladbach  |
: |  Bayer 04 Leverkusen
|
5:4 n.P., 1:1 (0:0) | |
| Wednesday, 27th October 2010 | 20:30 Uhr | SV Elversberg  |
: |  1. FC Nürnberg
|
0:3 (0:1) |
